UCR Spinoff Basilard BioTech Featured in Reputed Journal ‘Nature’ for its Gene-Delivery Innovation

By: Sharjeel Sohaib

β€’ 

Jul 14, 2022

 β€’ 

UCR Spinoff

Utilize Our Platform

Basilard BioTech was featured in Nature Journal due to its remarkable use of nanotechnology. The University of California (UC) Riverside spin-off, Basilard BioTech (basilardbiotech.com), views its “deterministic mechanoporation” technology as the pivotal point of its gene-delivery innovation. In this method, each cell is “poked” by a nanomechanical element (a silicon nanoneedle) only once, not randomly.

How Nanotechnology Will Change Our Lives

The era of nanomedicine is just beginning. Soon, nanoparticles and nanodevices will serve as precise medication delivery systems, cancer treatment equipment, or miniature surgical instruments.

Check out this video to know four ways in which nanotechnology can change our lives:

What are Nanoneedles?

Nanoneedles, which are vertical arrays of high-aspect-ratio nanomaterials, have become one of these nanotechnologies and have shown to be a straightforward, controlled, and effective technique for effectively accessing cells with little disturbance. 

Nanoneedles are quickly becoming viable alternatives for sensing and provide a way to revolutionize gene and cell therapy. The transformational potential of nanoneedles is still being realized. The Journal of Nature examines the rapidly developing innovations and robust commercial operations of nanoneedle technology from top academics, businesspeople, and venture investors; all are significant contributors to developing a workable nanoneedle technology for medical applications.

Why are Nanoneedles Becoming an Important Part of Science?

Access and transportation inside the cramped, dynamic environment of the cell are tightly controlled. Standard intracellular delivery and sensing techniques severely disrupt cell function, which limits their physiological applicability. 

The ingenuity of nanoneedles lies in their ability to enter various cell types repeatedly while causing minimum and temporary disturbance, allowing for the effective administration of sophisticated therapies (nano injection) and non-destructive cell state sampling (nano biopsy). The commercial interest in nanoneedles has increased due to their success in the lab, and start-ups seeking to create and use nanoneedle goods and services have seized this opportunity.

How Basilard BioTech is Utilizing Nanotechnology?

The University of California (UC) Riverside spin-off Basilard BioTech (basilardbiotech.com) views its “deterministic mechanoporation” technology as the pivotal component of its gene-delivery innovation. In this method, each cell is “poked” by a nanomechanical element (a silicon nanoneedle) only once and not randomly. The consistent, dependable, and less-disturbing delivery of genetic material is promised by this repeatable mechanical portion by a single needle on a single cell in the same area, which is an essential objective for CAR T-cell technology. The co-founders of Professor Masaru Rao and Mr. Brynely Lee believe that their technique will significantly change cellular immunotherapies, particularly CAR T-cell treatment.

A Glimpse of Basilard BioTecg Nanomechanical Gene Delivery

Basilard BioTech – Transforming the Cell-Based Therapies

Startempire Wire also reported that CellettoTM, the company’s innovative gene delivery technology platform, was unveiled in 2019. This unique technique for nanomechanical gene delivery has the potential to overcome the present limits of viral and non-viral gene delivery, paving the way for more scalable and cost-effective cell and gene therapy manufacturing.

We Covered this in our Weekly Wire Roundup

Wrap Up

The approach developed by Basilard BioTech is exceptional for its singular ability to precisely and securely produce a single pore in both the plasma and nuclear membranes of every cell in a large population. This is effective because it helps intranuclear administration via direct injection, high cellular viability and delivery efficiency, and uniform treatment of all cells.

Check out the complete article about nanotechnology at: https://www.nature.com/articles/s41565-022-01158-5

Related: We have covered the news of how the Wet Lab Incubator will help the Biotech startup ecosystem in the Inland Empire. Read more about that

0 Comments

Submit a Comment

Connecting you with the best startups, people & events in the Inland Empire.

Support Startup News & Media!


Enjoying the startup news & media? Support us!

We have big plans, and we need your help!

Startempire Wire is a community of people working together to promote innovation, entrepreneurship, and investment in the Inland Empire. We provide resources and connect people with the startup culture.

We believe that the Inland Empire has all of the ingredients for success. This region just needs a platform to show the world what it can do – And this is exactly what Startempirewire.com is doing. Our goal is to act as a megaphone to connect the dots between the best startups, events, and people in the Inland Empire.

We have big plans, and we need your help! If you are passionate about creating a thriving local startup ecosystem, then we would like to invite you to join in contributing to the community by supporting us. You can do that by supporting us financially or by being an active contributor. In return, we will give you (depending on sponsorship level) free access to our content, other level based perks &Β  the opportunity to connect with a network of passionate people working to build a better future for all of us.

We cover the good and the bad of entrepreneurship, startups & business events; we do it with passion and purpose. If you like what we do, support us & please consider becoming a patron. Your support is essential for independent local startup media to survive & thrive.

You can make a regular one time donation to become a sponsor at any level, or you can choose to become a monthly or event sponsor.Β  Every little bit counts! Thank You

Verious B. Smith III

Founder, Startempire Wire

Related Articles

CTR and Fuji Electric team up for Hell’s Kitchen Geothermal . . .

CTR and Fuji Electric team up for Hell’s Kitchen Geothermal . . .

Controlled Thermal Resources (CTR) and Fuji Electric Corp. of America (FEA) recently signed a Memorandum of Understanding for the completion of several Equipment, Procurement, and Construction (EPC) contracts. The contracts will deliver multiple geothermal power...

China Airlines Boosts Recovery of International Air Service with  . . .

China Airlines Boosts Recovery of International Air Service with . . .

Ontario International Airport in California has announced that China Airlines will fully restore daily round-trip service between Southern California's Ontario International Airport (ONT) and Taipei beginning March 26, 2023. The resumption of daily service comes after...

Riverside and San Bernardino Clinics to Benefit from Pair Team, a . . .

Riverside and San Bernardino Clinics to Benefit from Pair Team, a . . .

Pair Team, a California-based nonprofit organization, is significantly impacting health clinics in San Bernardino and Riverside counties. Pair Team aims to provide underserved communities with quality healthcare, education, and technology resources. By partnering with...

Stay Up On Startempire News

Access Premium Content

Startempire Wire premium content access is free during the beta period of ourΒ  website.Β  Join during beta and get a grandfathered discount when we launch.

$5 for first month then $15 per month

Get Every Update

Would you like to receive Startempire Wire updates in your inbox? Subscribe below!

"*" indicates required fields

This field is for validation purposes and should be left unchanged.

Follow Us

Follow Startempire Wire on other social media channels.

My cart
Your cart is empty.

Looks like you haven't made a choice yet.